Aleix Espargaró crashed in the early stages of the Valencia GP, a race troubled by the rain - and decimated by the numerous crashes - which also forced officials to wave the red flag and schedule a second start for the riders who had managed to stay in the saddle. After a weekend consistently among the best, in warm up Aleix confirmed his performance with a brilliant second place time, demonstrating his competitiveness in the wet and the progress made by the RS-GP evolution brought to the race in the final rounds of the championship. Starting from the eighth spot on the grid, Aleix maintained the position, preparing for a race which, in heavy rainfall, promised to be long and difficult. However, on the third laps, the asphalt conditions betrayed him and his race ended early in the gravel. It is an outcome that leaves a bitter taste because of a result that went up in smoke and which, given the trend throughout the weekend, would have been well within his potential.

After the interruption in the fourteenth lap due to the increasing rainfall, Scott Redding started from the ninth spot at the second start and finished eleventh.

The Valencia race saw the Aprilia RS-GPs of Espargaró and Redding in livery (RED), to raise awareness among MotoGP enthusiasts about the issue of HIV, one of the great evils of our time. Since its foundation (RED) has contributed over 500 million USD to the Global Fund to fight HIV. (RED)'s aid has had an impact on 110 million people through prevention, treatment, counseling and support services, with a focus on countries with a high proportion of the HIV virus transmitted from mother to child.